Project Guided:

1. Identification of dormant Peptides/Proteins from non-coding regions of selected bacterial genome.

2. Identification of small RNAs and their human genomic targets from non-coding regions of selected bacterial genome

3. Preparation of a dataset for potential lead compounds for treating MDR-TB using structural analysis and docking approach

4. Docking study to find potential drug candidate to treat Acute Myeloid Leukemia (AML) by targeting FLT3 receptor

5. Docking study to find potential drug candidate to treat Oral cancer

6. Docking study of estrogen receptor alpha (ERa) protein to find its binding energy with potent inhibitors similar to breast cancer drugs

7. Quantitative Structure-Activity Relationship (QSAR) modeling for the analysis of Estrogen Receptor Beta modulators

8. Sequence Homology and SNP Detection in Abiotic Stress Responsive Genes in Rice.

9. Study of the implications of copy number variation on Human populations: “The Causes and consequences".

10. Study of LC/GC-MS based plant metabolomics data processing and analysis.

 

Other Projects:

 

B.E. Project:

• Study of Antioxidant and Antimicrobial Properties, Phytochemical screening and analysis of Sap Extracted from Banana Pseudostem (Jan 2011 – June 2011).

         Extraction of sap from banana pseudostem, Antioxidant analysis of the sap using phosphomolybdenum reduction assay, Phytochemical analysis                               (Qualitative and Quantitative) of the sap, Antimicrobial (Antifungal and Antibacterial) analysis of the sap by disc diffusion and well diffusion method.

 

M.Tech. Projects:

• Identification and validation of Metadata, GC/LC-MS data Preprocessing and analysis methods for Plant metabolomics LIMS development. (May 2012 – July 2012)

         Based on “Metabolomics Standard Initiative” (MSI) standard, Identification of minimum parameters to be reported in order to define details of                                 experimental study designs in plant metabolomics studies. Further, study of GC/LC-MS data preprocessing and analysis methods specifically for plant                     metabolomics.

 

• Computational methods and algorithms for plant metabolomics data analysis: Normalization (Aug 2012 – Dec 2012)

         Study of algorithms involved in different normalization methods for metabolomics data. Identification and validation of open source/web-based/commercial           tools and R-packages available for data normalization.

​

• Identification and validation of NMR-based metabolomics 1D data pre-processing methods and softwares/R-packages (Jan 2013 – Feb 2013)

         Identification and validation of methods, softwares and R-Packages available for NMR Data preprocessing.

​

• Identification and validation of softwares/R-package for multi-dimensional NMR data processing and bio-profiling. (March 2013 – May 2013)

         Identification of steps, general pipeline and R-Package for multi-dimensional NMR data preprocessing and analysis. Open source plant metabolite libraries             for NMR. Identification of the best tool/R-package and incorporation of individual steps in LIMS portal.

​​

• Mini Projects

  • Personal home page project on PHP and MySQL.

  • Development of Home page for the DBT, Govt. of India funded Project entitled “Computational Core for Plant Metabolomics”.

  • Created a Literature portal for CCNSB, IIIT-Hyderabad and a Wiki portal for “Computational Core for Plant Metabolomics” project.

​